• Lafayette "Lafe" Augustus Shadley (1844-1893) - Sheriff of Montgomery County, Kansas and later appointed as a U.S. Deputy Marshal in Oklahoma Territory. Shadley was killed in the line of duty in the Ingalls, Oklahoma gun battle with the Doolin-Dalton Gang.M.A. Shaffenburg - Served as a marshal in the Colorado Territory during the 1860s.

• Mike Sharp - A deputy sheriff of Val Verde County, Texas in 1909 under Sheriff C.C.
  Bartley.

• J.J. Sheridan - A U.S. Deputy Marshal in New Mexico Territory during the 1890s.

• Charles A. Shibell (1841-1908) - Pima County, Arizona sheriff from 1876 to 1880.

• Ed Short (18??-1891) - Served as a lawman in Stevens County, Kansas in 1888, a time when the county was embroiled in a vicious county seat war. Next, he served as a U.S. Deputy Marshal, in Oklahoma, and in August, 1891 arrested Charles Bryant, a member of the Dalton Gang. As he was transporting Bryant to the federal district court in Wichita, Kansas, the pair got into a gunfight and both were killed.

• Albert Sieber (18??-1907) - A U.S. Deputy Marshal and Indian scout, he employed at different time the Apache Kid, Frank Leslie, and Tom Horn. He died in 1907.

• Edward A. Sieker - Served as a Texas Ranger in Company D under Dan Roberts and led the attack against the Jesse Evans Gang in 1880.

• Frank Sieker (18??-1885) - Served in the Texas Rangers in Company B and was shot and killed in a battle with Mexican horse thieves in May, 1885.

• Lamartine "Lamb" P. Sieker (18??-1914) - Served in the Texas Rangers in Company B  and in 1884 was made quartermaster general. He served as a Ranger for nineteen years and died in 1914.

• Tom Sieker - Served as a Texas Ranger.

• Charles Sims (1879–1945) - Rosedale, Oklahoma Town Marshal.

• Pink Simms - A cowboy and lawman, he pursued the Wild Bunch with Charles Siringo.

• Benjamin Sippy - Served as city marshal of Tombstone, Arizona until January, 1881, when he was replaced by Virgil Earp. However, in the next election, Earp lost to Sippy.

• Charles Angelo Siringo (1855-1928) – A gunman and one of the most famous detectives of the Pinkerton National Detective Agency, Siringo also served as a lawman for many years and became an author. He died in California in 1928..

• Sam Sixkiller (1842-1886) - A Captain of the U.S. Indian Police and U.S. Deputy Marshal in Indian Territory.

• Joe Sitters - Served in Company D of the Texas Rangers in 1894.

• "Texas" John Horton Slaughter (1841–1922) - A Texas Ranger, Slaughter later moved on to become the Cochise County, Arizona Sheriff  where with his six-shooter and sawed off shotgun, cleaned up Arizona Territory more than any other single individual. He died on February 15, 1922.

• Colonel Smith - Colonel of the Texas Rangers of Headquarters Company of Austin, Texas in 1919.

• James L. "Whispering" Smith (18??-1914) - A gunfighter and a lawman, Smith served as New Orleans Police Detective, Railroad Detective for several companies, stock detective, Chief of Indian Police.

• J.D. Smith - Served as a U.S. Deputy Marshal in the New Mexico Territory, and was shot to death while in pursuit of the outlaw Samuel Ketchum.

• Simeon H. Smith - Served as a U.S. Deputy Marshal in the New Mexico Territory during the 1850s.

• Thomas J. Smith, aka: Bear River (1830–1870) - Served as Kit Carson, Colorado Marshal; a police officer in Bear River, Wyoming during the "Bear River troubles;" and as first marshal of Abilene, Kansas in 1870, where he was known as the "No gun marshal." On November 2, 1870, he was shot and killed while trying to arrest a murderer.

• William Smith - Served as a U.S. Deputy Marshal in Indian Territory in the 1880s and 1890s.

• W.J. Snearly - Served as a Texas Ranger in 1877 under Pat Dolan and was one of his most efficient men.

• A.J. Sowell (18??-1922) - Served as a Texas Ranger in 1870-71, and later wrote and published several Texas history books.

• Wells Spicer (18??-1885) - Related to the Earps, Spicer was serving as Tombstone's Justice of the Peace at the time that the Gunfight at the O.K. Corral took place. After Sheriff Johnny Behan arrested the Earp brothers - Virgil, Wyatt, and Morgan, as well as Doc Holliday, a pre-trial hearing was held on November 29, 1881 where Spicer decided that the defendants had been justified in their actions.

• A. John Spradley - Served as deputy sheriff of Nacogdoches County, Texas in 1880 under Sheriff Dick Orton and was elected sheriff in 1881.

• Wiley W. Standefer - A lawman, he served as U.S. Marshal of the Arizona Territory from Aug. 15, 1876, until June 12, 1878.

• R.M. Stephens - Served as a sheriff in the New Mexico Territory during the 1850s.

• Con Stapleton (1848–1879) - Stapleton was made Deadwood, South Dakota Marshal shortly after Bill Hickok was shot by Jack McCall. Later he moved to Leadville, Colorado and was found dead in Denver in 1879.

• Frank C. Stillwell (1857-1882) - Known as both a lawman and an outlaw, Stillwell hooked up with the Clanton Gang and began cattle rustling. Thief or no, Johnny Behan appointed him as a Cochise County Deputy Sheriff in 1881. He was killed by the Earps in 1882.

• Simpson "John" Stilwell, aka: Commanche Jack - A gunman and lawman, he scouted for the Army in Texas before serving as a U.S. Deputy Marshal in Indian Territory.

• Port Stockton, (William Porter, AKA: Porter Stogden) - An outlaw, lawman, and brother of Ike, he  shot and killed Juan Gonzales in October 1876 in Cimarron, New Mexico, and was killed on January 10, 1881 by Alfred Graves.

• Dallas Stoudenmire (1845–1882) - A lawman and gunfighter, Stoudenmire joined the Texas Rangers in 1874 and was city marshal of EI Paso, Texas in 1881. He killed several men in that capacity. In 1882, he resigned as marshal and became a U.S. Deputy Marshal. He was killed on September 18, 1882 by James and Doc Manning in El Paso.

• Michael Sughrue (1844-1901) - Deputy under twin brother and sheriff Patrick Sughrue in Dodge City, Kansas, he later served as Clark County, Kansas sheriff. Both he and his brother  were seen as two of the most courageous lawmen in the west.

• Patrick F. Sughrue (1844-1906) - Dodge City, Kansas lawman during the final days of the cattle era and twin brother to Michael Sughrue, also a Kansas lawman. Both men were seen as two of the most courageous lawmen in the west.

• W. John L. Sullivan - Derved as a sergeant in Company B of the Texas Rangers.

• Jesse Sunday - Served as sheriff of the Sabine district in the Cherokee Nation of Indian Territory in the late 1880s.

• William E. “Billy” Sutton (1846-1874) - A gunfighter and lawman, Sutton was the leader of a band of “Regulators” in DeWitt County, Texas involved in the Sutton-Taylor feud.

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